Aspirin in antiphospholipid syndrome

Desensitisation to aspirin in antiphospholipid antibody syndrome.

cases. Patch testing with a battery of sunscreens gave a positive reading (++) at 48 and 96 h to butyl methoxydibenzoylmethane 2% (Parsol 1789) in both cases (Fig. 1). Since only one of the sunscreens contained parsol, we decided to test with other sunscreens. The results are shown in Table 1. All sunscreens that gave a positive patch test reaction contained octocrylene, which is included in so...

Aspirin thromboprophylaxis of asymptomatic antiphospholipid-positive subjects.

The appropriateness of aspirin prophylaxis to prevent the occurrence of thrombosis in asymptomatic patients with confirmed positivity of antiphospholipid antibodies (aPL) has been recently debated. On the one side, Meroni and his group [1] support the reasons in favor of aspirin administration, particularly to patients considered at high risk of thrombosis. These patients are identified as thos...

Anticardiolipin syndrome: antiphospholipid syndrome.

North Am 2000;26:215–27. 14 Savill J. Recognition and phagocytosis of cells undergoing apoptosis. Br Med Bull 1997;53:491–508. 15 Elkon KB. Apoptosis in SLE – too little or too much? Review. Clin Exp Rheumatol 1994;12:553–9. 16 Drappa J, Vaishnaw AK, Sullivan KE, Chu JL, Elkon KB. Fas gene-mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmu...

Antiphospholipid syndrome

APS can be primary or secondary. Primary antiphospholipid syndrome occurs in the absence of any other related disease. Secondary antiphospholipid syndrome is often associated with systemic lupus erythematosus and less frequently with infections, drugs and other diseases. Serologic markers are antiphospholipid antibodies, lupus anticoagulant and anticardiolipin. In rare cases, APS leads to rapid...

Antiphospholipid syndrome